Elenco - Holmes e Watson
Will Ferrell
Sherlock Holmes
John C. Reilly
Dr. John Watson
Rebecca Hall
Dr. Grace Hart
Kelly Macdonald
Mrs. Martha Hudson
Rob Brydon
Inspector Lestrade
Lauren Lapkus
Millie
Pam Ferris
Queen Victoria
Ralph Fiennes
Prof. James Moriarty / Jacob Musgrave
Adam Scherr
Brawn
Kieran O'Brien
PC Smalls
Noah Jupe
Doxy
Bella Ramsey
Flotsam
Colby Mulgrew
Haybag
Scarlet Grace
Pickle
Billy Jenkins
Mud Fog
Michael Culkin
The Judge
Jana Pérez
Lestrade's Wife
Wolf Roth
Sigmund FreudNathan Osgood
Mark TwainDavid Shackleton
Albert Einstein
Paul Cassidy
Charlie Chaplin
Ben Lee
Houdini
Bronson Webb
Jonathan NightingaleJamie-Rose Monk
Mrs. Nightingale
Billy Zane
Billy Zane
Jason Thorpe
Butler
Robert Cawsey
WaiterStanley Eldridge
Waiter
Oliver Maltman
Telegraph Operator
David Stoller
Hudson's GuardJack Riley
Newschild
Lilly Aspell
Newschild
Ethan Rouse
NewschildEllie Rose Eames
Newschild
Jamie Baughan
Titanic Ship Officer LiaisonHelen Duff
Titanic Guest